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How does the endocannabinoid system work?
Sep. 15, 2023 by SOMAÍ
How does the endocannabinoid system work?
The ECS is made up of three core components:
1 Endocannabinoids, also referred to as endogenous cannabinoids, that are molecules made by your body
2
Cannabinoid
receptors
3
Enzymes that synthesise
and degrade
endocannabinoids
1 Endocannabinoids
Endocannabinoids are chemical messengers that bind to cannabinoid receptors to signal that the ECS needs to take action. They are similar to cannabinoids, except that they are produced by your body.
There are two key endocannabinoids that have been identified:
- Anandamide (AEA)
- 2-arachidonoyglyerol (2-AG)
These chemical messengers keep internal functions running smoothly and are produced by your body as and when they are needed.
2 Cannabinoid receptors
Cannabinoid receptors can be found throughout your body. To-date, two cannabinoid receptors that have been studied: CB1 and CB2. CB1 receptors can be found in abundance in the central and peripheral nervous system, as well as the gastrointestinal tract and skeletal system. CB2 receptors, on the other hand, are mostly located in the peripheral nervous system, particularly immune cells. Endocannabinoids can bind to either receptor. The influence that this has depends on where the receptor is located, and which endocannabinoid binds to it.
CB1 receptors influence pain, sleep, appetite, and memory, and mediate most psychoactive effects of cannabinoids. On the other hand, CB2 receptors are primarily involved in anti-inflammatory and immunosuppressive actions.
3 Enzymes
Enzymes are responsible for synthesising and breaking down endocannabinoids once they have carried out their function.
There are two main enzymes that are responsible for the degradation of endocannabinoids:
- Fatty acid amid hydrolase, which breaks down endocannabinoid AEA
- Monoacylglycerol lipase, which typically breaks down 2-AG
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Yahoo Finance LISBON, Portugal, Nov. 10, 2021 (GLOBE NEWSWIRE) -- SOMAÍ Pharmaceuticals Unipessoal LDA has received an innovative products grant...
SOMAÍ Pharmaceuticals awarded €2.7M in funding from Portugal 2020 Grant
AP News LISBON, Portugal, Nov. 10, 2021 (GLOBE NEWSWIRE) -- SOMAÍ Pharmaceuticals Unipessoal LDA has received an innovative products grant...
SOMAÍ Pharmaceuticals awarded €2.7M in funding from Portugal 2020 Grant
Opera News LISBON, Portugal, Nov. 10, 2021 (GLOBE NEWSWIRE) -- SOMAÍ Pharmaceuticals Unipessoal LDA has received an innovative products grant...
SOMAÍ Pharmaceuticals awarded €2.7M in funding from Portugal 2020 Grant
Profiles in Legalization LISBON, Portugal — SOMAÍ Pharmaceuticals Unipessoal LDA has received an innovative products grant of 2.7 million euros...
SOMAÍ Pharmaceuticals bénéficie d’un financement de 2,7 millions d’euros de Portugal 2020
La Bourse Et La Vie LISBONNE, Portugal, 10 nov. 2021 (GLOBE NEWSWIRE) — SOMAÍ Pharmaceuticals Unipessoal LDA a reçu une...
Somai: The Global Story of Cannabis
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SOMAÍ Pharmaceuticals at MJUnpacked: What Markets And Geography Does Somai Pharma Address?
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SOMAÍ Pharmaceuticals at MJUnpacked: What Should Consumers, Other Brands And Investors Know About The Future Of Somai Pharma
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SOMAÍ Pharmaceuticals at MJUnpacked: Tell Us About Your Company And What Makes You Different
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These Are The Cannabis Industry’s Biggest Tricks and Treats So Far
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Michael Sassano: GMP Series #7: Personnel Recruitment
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Why Germany is Not the Future Leader of European Cannabis
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Michael Sassano CEO and Chairman Somai Pharmaceuticals: GMP Series #5: ERP Implementations
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The Advantages of Ethanol Extraction
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Does Big Business Provide A Better Look Into Cannabis Reform Than Capitol Hill?
Business Insider Operators in various sectors of cannabis feel that the industry provides a better insight into regulatory needs and...
Does Big Business Provide A Better Look Into Cannabis Reform Than Capitol Hill?
The Fresh Toast Operators in various sectors of cannabis feel that the industry provides a better insight into regulatory needs...
Does Big Business Provide A Better Look Into Cannabis Reform Than Capitol Hill? Operators Believe So.
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Cannabis Stocks Next Big Wave Is Coming Late August
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CANNA WORLD EXPO EUROPEAN UPDATE SOMAI PHARMACEUTICALS CEO MICHAEL SASSANO
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Beyond CBD, THC: ‘Minor’ Cannabinoids Flood Market — Lack of data is concerning, even for practitioners who believe in medical cannabis
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Benzinga When the COVID-19 pandemic hit the world by surprise last year, cannabis businesses around the world faced the uncertainty...
SOMAÍ Pharmaceuticals Bringing The Future Of European Cannabis Market
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Low-Cost Pot Stocks To Consider, According To SOMAÍ Pharmaceuticals CEO Mike Sassano
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Benzinga Cannabis Capital Conference | February 25-26, 2021 | Michael Sassano
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PREDICTIONS | Want to know the future? There are two ways: a crystal ball or really smart people (pages 74-75)
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These Are The Top European Cannabis Companies
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UK to see largest medical cannabis market growth in Europe 2020 to 2025
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Desert Oasis | Solaris Farms is capitalizing on a prime location and plenty of Nevada sunshine (page 58-61 November issue)
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Cannabis Top 20: North America’s Largest Commercial Grows
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Real Deals – Michael Sassano
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Best practices for securing your cannabis grow operations and supply chains
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Cannabis Terpenes: What Growers Need to Know
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California joins push to let cannabis businesses use banks as part of coronavirus relief
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Lawmakers Look to Include Cannabis Banking Reform in Next COVID-19 Stimulus Bill
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COVID-19 Is Leaving Its Mark On The Cannabis Industry, Insiders Say
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Why Cannabis Will Boom During the “New Normal”
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Cannabis Do-Gooders: These Companies Are Lending A Helping Hand Against COVID-19
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Cannabis Do-Gooders: These Companies Are Lending A Helping Hand Against COVID-19
Yahoo finance "Recently, in-order to give back to the community and create outward good will, Solaris Farms reduced pricing to...
Hemp Companies Step Up To Help During Pandemic
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Cannabis Pros Sound Off On How Coronavirus Pandemic Will Affect Industry
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CannaBusiness Tips For Coronavirus Times
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Cannabis Executives on Turbulent Markets: “Don’t Panic”
Equities “I’m a believer in letting the flood gates open. But I see things from a well established position. The...
Michael Sassano: the man bringing US cannabis know-how to Europe
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Michael Sassano: the man bringing US cannabis know-how to Europe
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Michael Sassano: the man bringing US cannabis know-how to Europe
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New Cannabis Products: Kiva’s Camino CBN Line, Solaris x Cannabis & Culture’s Line And A Topical Cream
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New Cannabis Products: Kiva’s Camino CBN Line, Solaris x Cannabis & Culture’s Line And A Topical Cream
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European Union Urges Member Nations to Vote for World Health Organization’s Cannabis Rescheduling Recommendations
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“Marijuana is a global trend that can no longer be stopped.”
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Which European Countries Cannabis Investors Should Watch in the New Decade
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‘Big Cannabis’ Technologically Ahead Of Its Times, But Post-Harvest Automation Remains Elusive
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U.S. leads in cannabis innovation, but cedes global market to Canada
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American pot is the gold standard. But Canada leads the export game — for now
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American pot is the gold standard. But Canada leads the export game — for now
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America’s marijuana growers are the best in the world, but federal laws are keeping them out of global markets
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What Should Investors Take Away From MJBizCon 2019?
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How to Do Cannabis Cultivation Business Planning for Growth
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“5 Things I Wish Someone Told Me Before I Started Leading a Cannabis Business”, with Michael Sassano and Len Giancola
Medium The cannabis business is a complete dedication and you must make large sacrifices for it. It is very fast...
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Vegas Hybrid GreenHouse Dominance by Mike Sassano – page 20
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The Cannabis Cultivation Costs by State
MG Retail Magazine To the outside world, the legal cannabis industry appears to be one big cash machine. While it’s...
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OZ WRITERS COUNCIL DIRECTORY
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Are cannabis hand-trimmers an endangered species?
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Automation and sensors in hybrid greenhouses
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Desert Greenhouse Cultivation
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Five Diverse Questions With Michael Sassano, Founder: Solaris Farms
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Automation is the Future of Cannabis
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How Solaris Farms’ Michael Sassano Works: Cannabis Workspace
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Federal Court Orders DEA to Explain Inaction on Cannabis Cultivation Applications
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Federal Court Orders DEA to Explain Why It Has Ignored Cannabis Cultivation Applications
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Soma Pharmaceuticals Reveals Plans for Ireland’s Medical Cannabis Market
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What Technology Will Most Impact The Cannabis Industry? 24 Experts Share Their Insights
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Solaris Farms Tackles Desert Heat with Global Tech
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What Trends Are Shaping The Cannabis Industry In 2019? 25 Experts Weigh In
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What’s The Future Of The Cannabis Industry? 28 Experts Share Their Perspectives
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CANNABIS INTERVIEW – MICHAEL SASSANO – FOUNDER SOLARIS FARMS
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Mike Sassano – A Cannabis Business in the Opportunity Zone
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Define “Organic”: The Cannabis Movement Is Stuck On Labeling
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